In 2018, the Centers for Disease Control and Prevention (CDC) awarded the Mississippi Public Health Institute (MSPHI) grant funding through one of thirty-one national REACH (Racial and Ethnic Approaches to Community Health) awards to address breastfeeding rates on the Gulf Coast. The overall purpose of the project entitled, “The Healthy Families, Mothers and Babies Initiative”, is to support Mississippi Gulf Coast communities in the implementation of strategies that improve health, prevent chronic disease, and reduce health disparities among African Americans who have the highest burden of chronic disease related to health risk behaviors. The project has implemented evidence-based interventions that are supported by a strong community-level stakeholder coalition. Interventions are aimed at African American women of child-bearing age and their families in an effort to improve birth outcomes, maternal health and infant health. Through the work of the established coalition, community members and organizations have been influenced to support improved nutrition with an emphasis on breastfeeding and increased access to healthy foods. In addition, community support has been increased for tobacco free living among mothers and their families. Expected outcomes for this project include a reduction in health disparities among the target population, reduced chronic disease rates, and improved clinical and community linkages.